Graziani is an Italian surname. Notable people with the surname include:

• Achille Graziani (1839–1918), Italian archaeologist
• Ariel Graziani (born 1971), South American footballer
• Augusto Graziani (1933–2014), Italian economist
• Ercole Graziani the Younger (1688–1765), Italian painter
• Francesco Graziani (1828–1901), Italian baritone
• Francesco Graziani (born 1952), Italian footballer
• Gaspar Graziani (died 1620), Voivode (Prince) of Moldavia
• Girolamo Graziani (1604–1675), Italian poet
• Giulio Cesare Graziani (1915–1998), Italian aviator
• Ivan Graziani (1945–1997), Italian singer-songwriter
• Izhak Graziani (1924–2003), Bulgarian-born Israeli conductor
• Lodovico Graziani (1820–1885), Italian operatic tenor
• Luis Arias Graziani (1926–2020), Peruvian air force officer and politician
• Rodolfo Graziani (1882–1955), high-ranking Italian military officer and political figure during the 1930s and 1940s
• Sergio Graziani (1930-2018), Italian actor and voice actor
• Tony Graziani (born 1973), American football player