The 2010 NCAA Division I Cross Country Championships were the 72nd annual NCAA Men's Division I Cross Country Championship and the 30th annual NCAA Women's Division I Cross Country Championship to determine the team and individual national champions of NCAA Division I men's and women's collegiate cross country running in the United States. In all, four different titles were contested: men's and women's individual and team championships.^[1][2]

2010 NCAA Division I Cross Country Championships
Organisers	NCAA
Edition	72nd–Men 30th–Women
Date	November 22, 2010
Host city	Terre Haute, IN
Venue	Indiana State University LaVern Gibson Championship Cross Country Course
Distances	10 km–Men 6 km–Women
Participation	246–Men 253–Women 499–Total athletes
← 2009 2011 →

Held on November 22, 2010, the combined meet was the seventh of eight consecutive meets hosted by Indiana State University at the LaVern Gibson Championship Cross Country Course in Terre Haute, Indiana. The distance for the men's race was 10 kilometers (6.21 miles) while the distance for the women's race was 6 kilometers (3.73 miles).

The men's team championship was again won by Oklahoma State (73 points), the Cowboys' second consecutive and third overall. The women's team championship was again won by Villanova (120 points), the Wildcats' second consecutive and ninth overall.

The two individual champions were, for the men, Samuel Chelanga (Liberty, 29:22.2) and, for the women, Sheila Reid (Villanova, 20:06.9).^[3][4]