Transparency Market Research (TMR) has published a new report titled, ‘Oligonucleotide Synthesis Market - Global Industry Analysis, Size, Share,
Growth, Trends, and Forecast, 2019–2027’. According to the report, the global a
market was valued at US$ 1,966.2 Mn in 2018 and is projected to expand at a
CAGR of 9.5% from 2019 to 2027.
Overview
·
An
oligonucleotide is a single-stranded chain composed of a number of nucleoside
units connected together by the process of phosphodiesterase, which typically
synthesizes small fragments on nucleic acid sequences up to 25 bases, with the
desired structure and a given sequence needed for different applications.An
oligonucleotide is a single-stranded chain composed of a number of nucleoside
units connected together by the process of phosphodiesterase, which typically
synthesizes small fragments on nucleic acid sequences up to 25 bases, with the
desired structure and a given sequence needed for different applications.
·
There
are various lengths of oligonucleotides, and sequences and design modifications
available. Thanks to the increasingly developing biotechnology and life
sciences markets, there has been a n ever-rising need for oligonucleotides on
the global market, as well as rising acceptance and use of oligonucleotides in
clinical and diagnostic fields.
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Technological Advancements in Synthetic Chemistry to Drive Market
·
The
advances in the technological development of organic molecules are expected to
drive the growth of the oligonucleotide synthesis market
·
The
advanced synthesis of oligonucleotides provides longer oligos with better
sequence fidelity and higher purity that can be used in a number of molecular
biology applications
·
Various
pharmaceutical and biotechnology companies are continuously working on developing newer and advanced
methods in synthetic chemistry
·
For
instance, Integrated DNA Technologies, leader of synthesized oligonucleotides has
developed various pioneered methods to synthesize oligonucleotides of extreme
lengths. The company has developed oligonucleotides up to 200 base length which
is used with mass spectrometry for the manufacture of mini-genes.
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Synthesized oligonucleotides Segment to Dominate Market
·
Based on
product type, the global oligonucleotide synthesis market has been divided into
reagents & consumables, equipment, and synthesized oligonucleotides. The
synthesized oligonucleotides segment has been bifurcated into DNA
oligonucleotides, RNA oligonucleotides, and others.
·
The
synthesized oligonucleotides segment dominated the global oligonucleotide
synthesis market in 2018 and the trend is projected to continue during the
forecast period. Synthesized oligonucleotides are widely used in research as
well as in therapeutics and diagnostics applications. Synthesized
oligonucleotides are ready to use oligonucleotides. These are also available as
customized oligos prepared as per need. There are two types of commercially
used synthesized oligonucleotide: DNA oligonucleotides and RNA
oligonucleotides. Bridged Nucleic Acid (BNA) and Locked Nucleic acid (LNA) are
the other types of synthesized oligonucleotides used in research.
Research Applications to be Highly Lucrative Segment
·
In terms
of application, the global oligonucleotide synthesis market has been classified
into research, diagnostic and therapeutic. Among the applications, the research
applications segment dominated the global oligonucleotide synthesis market in 2018.
Rising R&D focus of pharmaceutical & biotechnology companies, along
with technological advances in the techniques such as polymerase chain
reaction, and next generation sequencing, are some of the major factors driving
the growth of the research segment in 2018. However, rising applications in
therapeutics, and growing R&D in RNAi therapeutic drugs is expected to
drive the growth of the therapeutic segment during 2019-2027
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North America to Dominate Global Market
·
In terms
of region, the global oligonucleotide synthesis market has been segmented into
North America, Europe, Asia Pacific, Latin America, and Middle East &
Africa. North America dominated the global Oligonucleotide Synthesis market in
2018, followed by Europe.
·
North
America accounted for major share of the global oligonucleotide synthesis
market in 2018, According to the data obtained from the ongoing clinical trials
in the oligonucleotides segment, there were more than 70 oligonucleotide
ongoing or recently completed trials in the U.S. alone. Fast growing life
science industry, rising focus on genetics and genomics in the research and
diagnostics applications in North America, and growing focus of pharmaceutical
organizations on oligonucleotides as therapeutic agents comprising RNAi and
antisense therapeutics are driving demand for oligonucleotides in North
America.
·
However,
rising focus on personalized medicine and growing biotechnology and life
science research activities in Asia Pacific, along with rising healthcare
spending on research & development in India, China, and Japan are factors
expected to boost the growth of the market for oligonucleotide synthesis in
Asia Pacific from 2019 to 2027.
Competitive Landscape
·
The
global oligonucleotide synthesis market is fragmented in terms of number of
players. Key players in the global market include GE Healthcare, Thermo Fischer
Scientific, Agilent Technologies, Inc., Merck KGaA, Integrated DNA
Technologies, Inc., Kaneka Eurogentec S.A., BioAutomation, Gene Design, Inc.,
Eurofins Genomics, and ATDBio, Ltd. among others.
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