Scaffolds are artificial extracellular matrices that
support 3D tissue regenerations and accommodate cells. These can be temporary
or permanent matrices which provide chemical, mechanical, and biological
support for tissue formation. Scaffold technology is employed to perform 3D
culture assays that include cell to cell interactions, high throughput
screening, cell to matrix interactions, transfections, and cell migration
assays. Growing regenerative technology has been attributed to the growth of
the scaffold technology market which has led to the development of
bio-scaffolds. Scaffolds act as a template for tissue formation, which are
subject to biophysical stimuli through a bioreactor, a system which applies
chemical and mechanical stimuli to the cells; or are provided with growth
factors.
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In terms of material, the scaffold
technology market can be segmented into bio-inert, bioresorbable, and
bioactive. Based on technology, the market can be segmented into
nanofiber-based scaffolds, polymeric scaffolds, hydrogels, and micro-patterned
surface microplates. In terms of application, the scaffold technology market
can be segmented into drug development, tissue culture, cancer treatment, stem
cell research, and regenerative technology. End-users in the scaffold
technology market include biotechnology and pharmaceutical organizations,
research laboratories, hospitals, and diagnostic laboratories. In terms of
region, the market can be segmented into North America, Latin America, Asia
Pacific, Europe, and Middle East & Africa.
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Scaffold technology provides opportunities to
address the challenges associated with tissue culture such as vascularization
and enable organ implant regeneration employed in the treatment of damaged and
diseased organs or tissues. Increasing number of applications would contribute
to the growth of scaffold technology market. In addition, rising accidents
leading to organ damage and increase in geriatric population that add to the
rising number of people with non-functioning of organs contribute to the growth
of the scaffold technology market. In addition, ongoing research on designing
matrix-based 3D substrates that enable interaction between implants and host
microenvironment for optimal functioning of the implanted cells and drug
release is expected to boost the market in terms of revenue during the forecast
period. However, the emergence of scaffold-free technology for cell culturing
is expected to hamper the scaffold technology market during the forecast
period.
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Hydrogels based scaffolds are expected to dominate
the scaffold technology market due to the continuous progress in their
development. However, nanofiber-based scaffolds are expected to record highest
growth rate during the forecast period, owing to the growing nanotechnology and
their ability to mimic nanoscale properties. Growing investments by
biotechnology companies for the development of products related to scaffold
technology is expected to contribute to the growth of the scaffold technology
market.
North America is expected to dominate the scaffold
technology market. Growth of the market in the region can be attributed to
well-developed infrastructure in the region, ongoing research, and the presence
of major market players in the region. However, the scaffold technology market
in Asia Pacific is expected to record the highest growth rate during the
forecast period, owing to the increasing government focus on boosting research
and development in the pharmaceutical industry and the improving health care
infrastructure in the region.
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Leading players in the scaffold technology market include
3D Biomatrix, 3D Biotek LLC, Acelity (LifeCell Corporation), Avacta Life
Sciences Limited, Becton, Dickinson and Company, Medtronic (Covidien plc),
Merck KGaA (Sigma-Aldrich Co. LLC), Molecular Matrix, Inc., Molecular Partners,
Nanofiber Solutions, NuVasive, Inc., Pelo Biotech GmbH, ReproCELL Europe Ltd.
(Reinnervate), Thermo Fisher Scientific, Inc., Vericel Corporation, and Xanofi.
The leading players in the market have been focusing on diversifying their
product portfolios and expanding their distribution networks to strengthen
their market position.
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