Ohio elected its member October 14, 1806. Both candidates were Democratic-Republicans, but from election articles published in The Scioto Gazette it was suggested that James Pritchard was the candidate of the Ohio Quids and that in a few counties, notably Columbiana and Jefferson, he was also supported by the Federalists.

District	Incumbent	Party	First elected	Result	Candidates[a]
Ohio at-large	Jeremiah Morrow	Democratic-Republican	1803	Incumbent re-elected.	Y Jeremiah Morrow (Democratic-Republican) 73.9% James Pritchard (Democratic-Republican/Federalist) 26.0%